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The analgesic activity of tramadol hydrochloride is because of the two parent drug and the M1 metabolite (seeCLINICAL PHARMACOLOGY, Pharmacodynamics). Tramadol is administered as a racemate and both the [-] and [+] sorts of equally tramadol and M1 are detected in the circulation. Tramadol is nicely absorbed orally with an complete bioavailability o